Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC755H1184N222O221S8

DescriptionStandard

        MVSKVQFNPRSRTDAIFVHCSATKPEMDIGVETIRMWHKQQAWLDVGYHFIIKRDGTVEEGRPVNVVGSHVKDWNSRSVGVCLVGGINAKGQFEANFTPAQMNSLRNKLDDLKVMYPQAEIRAHHDVAPKACPSFDLQRWLSTNELVTSDRG
    

Molecular Weight17163.35 Da

Isoelectric Point (pI)8.49

Net Charge (pH 7.0)2.01

Net Charge (pH 7.4) 1.42

Charge Density (pH 7.0) 0.0132

GRAVY Index-0.43

Hydrophobic Moment 0.57

Boman Index-0.05

Instability Index46.25

Aliphatic Index 75.59

Aromaticity 0.0789

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7149.13

LogP -73.51

H-bond Donors 249.0

H-bond Acceptors 237.0

Rotatable Bonds 567.0

Heavy Atoms 1206.0

Ring Count 29.0

Amide Bonds 166.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0095925 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage K1F [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic