Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC421H706N130O143S8

DescriptionStandard

        MRTLAILAAILLVALLAQAESLQETANNTATQEQPGEEDQDLAVSLEENGLSTLRASGSRATVTCYCRTGCCLLRETYSGSCNINGRIHRLCCR
    

Molecular Weight10133.41 Da

Isoelectric Point (pI)5.27

Net Charge (pH 7.0)-2.46

Net Charge (pH 7.4) -2.85

Charge Density (pH 7.0) -0.0262

GRAVY Index-0.05

Hydrophobic Moment 0.64

Boman Index-0.02

Instability Index48.08

Aliphatic Index 95.64

Aromaticity 0.0213

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4452.75

LogP -57.03

H-bond Donors 164.0

H-bond Acceptors 150.0

Rotatable Bonds 342.0

Heavy Atoms 702.0

Ring Count 4.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0236705 VERIFIED: NO

Provenance & Taxonomy

OrganismColobus angolensis palliatus [Animal]

FamilyDefensin

Tax ID336983

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence