Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC462H725N125O131S9

DescriptionStandard

        MRTSLFLFAVFFFLAPARSGFFDEKCYKLKGKCIESCQINEELIGLCQKSLKCCVALQPSTRMTQLHLGTRSYCNQQTSSSLSGHHQPLPTY
    

Molecular Weight10415.04 Da

Isoelectric Point (pI)8.95

Net Charge (pH 7.0)4.70

Net Charge (pH 7.4) 4.21

Charge Density (pH 7.0) 0.0510

GRAVY Index-0.10

Hydrophobic Moment 0.47

Boman Index0.03

Instability Index46.36

Aliphatic Index 74.24

Aromaticity 0.1087

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4124.70

LogP -42.19

H-bond Donors 150.0

H-bond Acceptors 148.0

Rotatable Bonds 345.0

Heavy Atoms 727.0

Ring Count 17.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0411194 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal