Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length288 amino acids

Chemical FormulaC1429H2247N369O412S11

DescriptionStandard

        MRVLQQELAKIHLPDFSGSTHTHLGKVKYSFNSMTIRNFQLPSSQISPVANVGLKLSISGAFIEISGKWHVKALHMSTKGGFDLKIEGLSISVGLKFGSDSTGRPTIALSDCSNHISDVKIHVSGKLSWLVDVFRHNVDNALRKAIENQICPLVSNAITSKLEPVLQTLPVTAKIDSVAAIDYSLTGPPPVTSDCVDVQMKGEFFELSHRVPPPFSPPTLTLPADHSLMIYFGVSDYLFNTAGFVYYSAGKLVFNVTDSMIPKEFNIRLNTSSFGVLIPQLSKMYPDM
    

Molecular Weight31541.07 Da

Isoelectric Point (pI)8.35

Net Charge (pH 7.0)2.36

Net Charge (pH 7.4) 1.53

Charge Density (pH 7.0) 0.0082

GRAVY Index0.08

Hydrophobic Moment 0.69

Boman Index0.14

Instability Index39.27

Aliphatic Index 95.38

Aromaticity 0.0868

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21555.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0368037 VERIFIED: NO

Provenance & Taxonomy

OrganismRanitomeya imitator [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria