Peptide Database

Peptide NameSLAY-screened peptide P3119

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC124H174N34O28

DescriptionStandard

        ELHHWNPAFVKLRSTWWGPIN
    

Molecular Weight2588.92 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)1.01

Net Charge (pH 7.4) 0.74

Charge Density (pH 7.0) 0.0481

GRAVY Index-0.58

Hydrophobic Moment 0.41

Boman Index0.10

Instability Index34.41

Aliphatic Index 74.29

Aromaticity 0.1905

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 984.33

LogP -4.72

H-bond Donors 34.0

H-bond Acceptors 31.0

Rotatable Bonds 75.0

Heavy Atoms 186.0

Ring Count 11.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326622 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/