Peptide Database

Peptide NameProadrenomedullin N-20 terminal peptide

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC111H175N35O28

DescriptionStandard

        ARLDVASEFRKKWNKWAVSR
    

Molecular Weight2447.79 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)3.80

Net Charge (pH 7.4) 3.60

Charge Density (pH 7.0) 0.1898

GRAVY Index-0.94

Hydrophobic Moment 0.53

Boman Index-0.35

Instability Index39.26

Aliphatic Index 63.50

Aromaticity 0.1500

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1069.71

LogP -8.91

H-bond Donors 40.0

H-bond Acceptors 32.0

Rotatable Bonds 82.0

Heavy Atoms 174.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0125148 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyProadrenomedullin N-20 terminal peptide

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Receptor modulation

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0238842 VERIFIED: NO