Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC229H372N60O71S3

DescriptionStandard

        MVKQQMNLVEIEAMNSLQELTLEELDNVLGAGGGVIQIHFIQTKQW
    

Molecular Weight5197.96 Da

Isoelectric Point (pI)4.41

Net Charge (pH 7.0)-4.40

Net Charge (pH 7.4) -4.68

Charge Density (pH 7.0) -0.0956

GRAVY Index0.03

Hydrophobic Moment 0.40

Boman Index0.16

Instability Index59.67

Aliphatic Index 114.35

Aromaticity 0.0435

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2141.63

LogP -17.91

H-bond Donors 69.0

H-bond Acceptors 71.0

Rotatable Bonds 182.0

Heavy Atoms 363.0

Ring Count 4.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0340596 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus infantis ATCC 700779 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence