Peptide Database

Peptide NameBrevinin-1Lb

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC120H201N27O27S4

DescriptionStandard

        FLPMLAGLAASMVPKFVCLITKKC
    

Molecular Weight2582.30 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.1141

GRAVY Index1.30

Hydrophobic Moment 0.55

Boman Index0.41

Instability Index30.52

Aliphatic Index 117.92

Aromaticity 0.0833

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 833.56

LogP -2.59

H-bond Donors 30.0

H-bond Acceptors 34.0

Rotatable Bonds 83.0

Heavy Atoms 178.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425750 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates pipiens [Animal]

FamilyBrevinin

Tax ID8404

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide18-24

Bio-Activity Profile

Function

Antimicrobial

TargetEscherichia coli

Activity16 μM

MethodMIC

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