Peptide Database

Peptide NameType VI secretion system tip protein VgrG

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1196 amino acids

Chemical FormulaC5888H9110N1664O1816S33

DescriptionStandard

        MDNWSALFDGQTRYGLDINDSTVKADVLRFRGREALSEPFNWDIEFTTLQANIPPEQVLMKYASFRMRSGKNVHGMVTRLEWLSTSRDQSHYQLTLSSRLALMGYTRQCAVYQNQSVPEVVEQVLRKHGLEGPDFEFRLERTYPPRELITQWRETDLQFIQRILSEVGIYWRTMMDDVRDLDTYIFADSQLNYQFDVRLPYSEPSGLFDGAAESVWDVRTWHNIATGTVATRNYNYRTATTPMDATVSVRSDAVTTGAHYRYAAPYREAGDDASPEPETETGAFYARIHHERELNRSARIHLFSNAAHLTPGQVLEPQGDVITALQEGVFLTLVTFRGARDSRLHVSVWGQPYTERYCFRPVEVPRPVIPGTLPARIESREKNDIYAHLDEQGRYRVKLDFDREGTESGYGYLWLRMAKPYAGETLGWHTPLTDGTEVAVAYSNSDIDLPYIAYALHDSEHPDHVNRDNHTRNVLRTPANNKLRMEDRRGEEHVRLATEYGKTQLNSGHLVDAQGQRRGTGAELRTDEWGTIRAGKGLFVSADAQPKAQGEVLDMSAALKEIDRLNQQLQQLEIAAEQAQALKADVDSQIQMFEQRLKPLNEAVFFSAPEGMALTSGEDMQLAAGQNLAVNAGGDISVGTMGNATLLTGEKLGLFARTGQLSLKSGEGPIDVQAQNASMRFFAEKKLTLSSASDISFVGKKRITLIGGGSYLRPEAGKVEYGTTASYMRKVKRTMAASARAKPPEAVSLPPPATMREFNPETLTPWVTPVYAKSCLKEKGCTDAGTAEEPVDNFGQMTIFAQPVEDDCCGYGHEHEHADDEVVQHAQSAKKRKSDAGGANAPAQATAAPLALGTATGVMTQVWGEWSLTGVLGAAWGIPYVGAMMSALYVPSAGEGSDRVPGRDEFWYEEELRQKAITGTKATTRVRFFWRQDEQGNMRVYGVHTGEGTPYEGVRTANMVWNSEHNQYEFTPAHGADGPLITWTPERPEGSDLPSHTGSDIKPIDQATILVTPIPDGKDEYTTPPFPVPEERDLNDYILVFPADSGIKPIYVYLKDDARNVPGEATGNGVKLSGDKPWLDMSVTNSGEGAPIPSQIADKLRGQKFNSFDDFRETIWNEIGRHPELTKDFTTVNKDRIEDGLAPWVPKEGQYIGPNSIVKKFAIHHVVPIKDGGGVYDMDNLRIVTSKLHDEIHYRR
    

Molecular Weight133321.53 Da

Isoelectric Point (pI)5.41

Net Charge (pH 7.0)-33.62

Net Charge (pH 7.4) -35.83

Charge Density (pH 7.0) -0.0281

GRAVY Index-0.54

Hydrophobic Moment 0.74

Boman Index-0.05

Instability Index33.47

Aliphatic Index 72.12

Aromaticity 0.0886

Extinction Coeff. Reduced 188050.00

Extinction Coeff. Oxidized 188425.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0174080 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyColicin/Bacteriocin

Tax ID28901

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence