Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC790H1189N179O241S8

DescriptionStandard

        QGIVYPAGNHSGPSYVAVPFTIPDQSDSMLYLAFSEYFFQTYSFAYYTAGAFNVAIAEETCSYFNISTEIFGSIIPEITKYSVTPYPVMLKLMATEMPIISLEQDSFTAEIQGSMEVFAVLPDSTTQSLFTTNIAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight17306.47 Da

Isoelectric Point (pI)4.07

Net Charge (pH 7.0)-10.15

Net Charge (pH 7.4) -10.48

Charge Density (pH 7.0) -0.0647

GRAVY Index0.27

Hydrophobic Moment 0.56

Boman Index0.26

Instability Index47.27

Aliphatic Index 85.80

Aromaticity 0.1401

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6647.34

LogP -61.59

H-bond Donors 227.0

H-bond Acceptors 240.0

Rotatable Bonds 547.0

Heavy Atoms 1218.0

Ring Count 32.0

Amide Bonds 170.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0074905 VERIFIED: NO

Provenance & Taxonomy

OrganismGeococcyx californianus (Greater roadrunner) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria