Peptide Database

Peptide NameBeta-defensin 119 (Beta-defensin 120) (Defensin; beta 119) (Defensin; beta 120)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC440H686N120O123S9

DescriptionStandard

        MKLLYLFLAILLAIEEPVISGKHHILRCMGNSGICRASCKKNEQPYLYCRNYQHCCLQSYMRISISGEEENTDWSYEKQWPRLP
    

Molecular Weight9913.47 Da

Isoelectric Point (pI)8.24

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.23

Charge Density (pH 7.0) 0.0204

GRAVY Index-0.34

Hydrophobic Moment 0.54

Boman Index-0.02

Instability Index70.37

Aliphatic Index 85.95

Aromaticity 0.1071

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3927.02

LogP -31.82

H-bond Donors 142.0

H-bond Acceptors 137.0

Rotatable Bonds 328.0

Heavy Atoms 692.0

Ring Count 18.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0044609 VERIFIED: NO

Provenance & Taxonomy

OrganismHylobates lar [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

RECORD: Rec_0227265 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Bacterium]

FamilyDefensin

Tax ID61853

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence