Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC164H270N52O57S2

DescriptionStandard

        RCNTATCATQRLVNFLSRSSNNLGAILSPTDVGSNTY
    

Molecular Weight3946.34 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.51

Charge Density (pH 7.0) 0.0470

GRAVY Index-0.21

Hydrophobic Moment 0.71

Boman Index-0.04

Instability Index33.82

Aliphatic Index 76.49

Aromaticity 0.0541

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1806.20

LogP -27.95

H-bond Donors 66.0

H-bond Acceptors 61.0

Rotatable Bonds 127.0

Heavy Atoms 275.0

Ring Count 3.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0114660 VERIFIED: YES

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)