Peptide Database

Peptide Name[Ser-7]-Sarafotoxin S6 a1

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC104H158N28O34S5

DescriptionStandard

        CSCKDMSDKECLNFCHQDVIW
    

Molecular Weight2504.86 Da

Isoelectric Point (pI)4.66

Net Charge (pH 7.0)-2.19

Net Charge (pH 7.4) -2.51

Charge Density (pH 7.0) -0.1042

GRAVY Index-0.35

Hydrophobic Moment 0.38

Boman Index-0.07

Instability Index89.56

Aliphatic Index 50.95

Aromaticity 0.0952

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1017.67

LogP -10.08

H-bond Donors 38.0

H-bond Acceptors 38.0

Rotatable Bonds 83.0

Heavy Atoms 171.0

Ring Count 4.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0155961 VERIFIED: NO

Provenance & Taxonomy

OrganismAtractaspis engaddensis [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0302025 VERIFIED: YES

Provenance & Taxonomy

OrganismAtractaspis engaddensis [Animal]

FamilySarafotoxin

Tax ID1343144

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Vasoactive Vasoconstrictor

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour