Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC400H618N108O114S8

DescriptionStandard

        MKLNPDSSTEFRPQEAAHTSYLVRLSVQLTYRSRVENEAASFPWSCPSLSGVCRKVCLPTEMFFGPLGCGKGFLCCVSHFL
    

Molecular Weight9020.36 Da

Isoelectric Point (pI)8.28

Net Charge (pH 7.0)1.63

Net Charge (pH 7.4) 1.20

Charge Density (pH 7.0) 0.0201

GRAVY Index0.01

Hydrophobic Moment 0.51

Boman Index0.07

Instability Index38.12

Aliphatic Index 69.75

Aromaticity 0.1111

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3519.13

LogP -35.87

H-bond Donors 129.0

H-bond Acceptors 126.0

Rotatable Bonds 286.0

Heavy Atoms 630.0

Ring Count 18.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0301817 VERIFIED: NO

Provenance & Taxonomy

OrganismAcanthochromis polyacanthus [Bacterium]

FamilyDefensin

Tax ID80966

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal