Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC242H388N62O75S5

DescriptionStandard

        MMKKDAIIESIKEVSLEELDQIIGAGNGVFKTISHECHLNTWAFLATCCS
    

Molecular Weight5526.36 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-3.34

Net Charge (pH 7.4) -3.72

Charge Density (pH 7.0) -0.0669

GRAVY Index0.21

Hydrophobic Moment 0.56

Boman Index0.17

Instability Index24.88

Aliphatic Index 97.60

Aromaticity 0.0600

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2198.43

LogP -19.75

H-bond Donors 78.0

H-bond Acceptors 79.0

Rotatable Bonds 189.0

Heavy Atoms 384.0

Ring Count 6.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049434 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus salivarius [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria

RECORD: Rec_0118234 VERIFIED: NO