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MYP_171372
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Basic Information
Las[C8-C27, C17-C25]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
27 amino acids
C129H238N38O28S4
Standard
Sequence
GLPRKILCAIAKKKGKCKGPLKLVCKC
Physicochemical Analysis
2897.77 Da
10.07
8.71
8.44
0.3227
0.07
0.62
-0.09
2.24
104.81
0.0000
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1072.40
-7.10
41.0
41.0
104.0
199.0
2.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0147787 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0165666 VERIFIED: YES
Provenance & Taxonomy
Lasioglossum laticeps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
8-25, 17-27
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
16 μM
MIC
PMID22038181 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22038181/
RECORD: Rec_0177651 VERIFIED: NO
Provenance & Taxonomy
Lasioglossum laticeps [Animal]
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
8-25; 17-27
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
RECORD: Rec_0186477 VERIFIED: YES
Provenance & Taxonomy
Lasioglossum laticeps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
8-17, 25-27
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
100 μM
MIC
PMID22038181 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22038181/
RECORD: Rec_0186796 VERIFIED: YES
Provenance & Taxonomy
Lasioglossum laticeps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
8-17, 25-27
Bio-Activity Profile
Hemolytic
Hemolytic activity
200 μM
LC50
PMID22038181 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22038181/
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