Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC546H873N147O161S3

DescriptionStandard

        PDLTGYEKYGLGNVKYNISRIHVTAVEFPSASISLLPGSGIKLVIGNASLTINMNWNIRTWMFKDSGRGAVHISKVFVTAIFSTPLGNAGPTSISLTSCRTPSGDIDIKLNGKT
    

Molecular Weight12168.86 Da

Isoelectric Point (pI)9.67

Net Charge (pH 7.0)5.12

Net Charge (pH 7.4) 4.93

Charge Density (pH 7.0) 0.0449

GRAVY Index0.07

Hydrophobic Moment 0.60

Boman Index0.15

Instability Index19.61

Aliphatic Index 94.91

Aromaticity 0.0789

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4906.86

LogP -53.68

H-bond Donors 174.0

H-bond Acceptors 171.0

Rotatable Bonds 397.0

Heavy Atoms 857.0

Ring Count 19.0

Amide Bonds 121.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0148403 VERIFIED: NO

Provenance & Taxonomy

OrganismPanurus biarmicus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria