Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length228 amino acids

Chemical FormulaC1148H1750N262O342S9

DescriptionStandard

        IDDLAKADYSLNSLPAVFQPFIDLDLKGTVYPAGNCSGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKHSVTPYPVMLKLMATEIPIISLEQDSFTVEIQGSMEVFAVLPDSTPQSLFTMNIAANTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight24982.31 Da

Isoelectric Point (pI)4.20

Net Charge (pH 7.0)-14.07

Net Charge (pH 7.4) -14.47

Charge Density (pH 7.0) -0.0617

GRAVY Index0.33

Hydrophobic Moment 0.55

Boman Index0.26

Instability Index49.48

Aliphatic Index 98.03

Aromaticity 0.1228

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0055851 VERIFIED: NO

Provenance & Taxonomy

OrganismPygoscelis adeliae [Animal]

FamilyBPI/LBP

Tax ID9238

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria