Peptide Database

Peptide NameBombinin-like peptide 1 (toads, amphibians, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC115H193N33O34

DescriptionStandard

        GIGASILSAGKSALKGLAKGLAEHFAN
    

Molecular Weight2581.96 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)1.85

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.0684

GRAVY Index0.43

Hydrophobic Moment 0.60

Boman Index0.27

Instability Index-8.74

Aliphatic Index 108.89

Aromaticity 0.0370

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1067.74

LogP -12.13

H-bond Donors 37.0

H-bond Acceptors 37.0

Rotatable Bonds 89.0

Heavy Atoms 182.0

Ring Count 2.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0408700 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

FamilyBombinin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

Target82 % inhibition Neisseria meningitidis 118V C

Activity20 μg/mL

MethodMIC

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