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MYP_171261
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Basic Information
Bombinin-like peptide 1 (toads, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
27 amino acids
C115H193N33O34
Standard
Sequence
GIGASILSAGKSALKGLAKGLAEHFAN
Physicochemical Analysis
2581.96 Da
9.70
1.85
1.59
0.0684
0.43
0.60
0.27
-8.74
108.89
0.0370
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1067.74
-12.13
37.0
37.0
89.0
182.0
2.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0227711 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial
100% inhibition Neisseria Iactamica 15215A
20 μg/mL
MIC
PMID1744108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1744108/
RECORD: Rec_0228609 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus Cowan1
3.4 μM
MIC
PMID1744108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1744108/
RECORD: Rec_0229834 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Yersinia pseudotubercolosis
0.8 μM
MIC
PMID1744108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1744108/
RECORD: Rec_0230091 VERIFIED: YES
Provenance & Taxonomy
Oriental fire-bellied toad [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
N. meningitidis strains 118V, 15240, 126E, N. gonorrhoeae, N. lactamica
PaperBombinin-like peptides with antimicrobial activity from skin secretions of the Asian toad, Bombina orientalis.
RECORD: Rec_0237622 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial Hemolytic
PMID1744108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1744108/
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