Peptide Database

Peptide NameNisin A

Function Ontology

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Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC140H240N40O46S6

DescriptionStandard

        ITSISLCTPGCKTGALMGCSLSTATCHCSIHVSK
    

Molecular Weight3412.03 Da

Isoelectric Point (pI)8.43

Net Charge (pH 7.0)1.88

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0554

GRAVY Index0.64

Hydrophobic Moment 0.29

Boman Index0.24

Instability Index27.52

Aliphatic Index 83.24

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1346.76

LogP -19.78

H-bond Donors 54.0

H-bond Acceptors 56.0

Rotatable Bonds 110.0

Heavy Atoms 232.0

Ring Count 3.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0414036 VERIFIED: YES

Provenance & Taxonomy

OrganismLactococcus lactis [Bacterium]

FamilyBacteriocin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)