Peptide Database

Peptide NameSLAY-screened peptide P3615

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC108H164N30O28S3

DescriptionStandard

        RCPYPFRLTCPCHYIVNKTD
    

Molecular Weight2426.84 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)1.82

Net Charge (pH 7.4) 1.51

Charge Density (pH 7.0) 0.0909

GRAVY Index-0.46

Hydrophobic Moment 0.43

Boman Index-0.11

Instability Index86.66

Aliphatic Index 53.50

Aromaticity 0.1500

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 929.66

LogP -7.46

H-bond Donors 35.0

H-bond Acceptors 34.0

Rotatable Bonds 70.0

Heavy Atoms 169.0

Ring Count 7.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0269664 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/