Peptide Database

Peptide NameGranulocyte colony-stimulating factor

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length175 amino acids

Chemical FormulaC842H1344N226O242S11

DescriptionStandard

        MAPLGPTGPLPQSFLLKCLEQMRKVQADGTALQETLCATHQLCHPEELVLLGHALGIPQPPLSSCSSQALQLMGCLRQLHSGLFLYQGLLQALAGISPELAPTLDTLQLDTTDFAINIWQQMEDLGMAPAVPPTQGTMPAFTSAFQRRAGGVLVASNLQSFLELAYRALRHFAKP
    

Molecular Weight18857.76 Da

Isoelectric Point (pI)5.89

Net Charge (pH 7.0)-3.09

Net Charge (pH 7.4) -3.66

Charge Density (pH 7.0) -0.0177

GRAVY Index0.15

Hydrophobic Moment 0.81

Boman Index0.17

Instability Index63.08

Aliphatic Index 99.37

Aromaticity 0.0571

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7335.12

LogP -77.41

H-bond Donors 247.0

H-bond Acceptors 255.0

Rotatable Bonds 607.0

Heavy Atoms 1321.0

Ring Count 31.0

Amide Bonds 193.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0295051 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyIL-6 superfamily

Tax ID9615; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide37-43; 65-75

Bio-Activity Profile

Function

Cytokine Growth factor IL-6 superfamily