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MYP_171187
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Basic Information
BF-30
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-Influenza A virus
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C62H106N18O12
Standard
Sequence
KFFRKKSVKK
Physicochemical Analysis
1295.62 Da
11.39
5.76
5.54
0.5755
-1.50
0.19
-0.68
6.12
29.00
0.2000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
537.45
-3.20
20.0
18.0
49.0
92.0
2.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008165 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 30447229 PMID30447229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30447229/
RECORD: Rec_0129559 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
influenza A virus H3N2: inhibition of viral replication in MDCK cells
7.36±1.2 μM
EC50
PaperPubMed PMID: 30447229 PMID30447229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30447229/
RECORD: Rec_0196814 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
MDCK cells
67
CC50
PaperPubMed PMID: 30447229 PMID30447229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30447229/
RECORD: Rec_0238544 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 30447229 PMID30447229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30447229/
RECORD: Rec_0257009 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
8613
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza A virus Replication inhibition
Influenza A virus H1N1 | MDCK cells
5.2±0.9 μM
EC50
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
PaperInhibition of peptide BF-30 on influenza A virus infection in vitro/vivo by causing virion membrane fusion. | Xu J, Chen S, Jin J, Ma L, Guo M, Zhou C, Dou J. | Peptides. 2019 Feb;112:14-22. | DOI:10.1016/j.peptides.2018.10.004 | PMID:30447229 PMID30447229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30447229/
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