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MYP_171185
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Basic Information
SmHep1P
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Standard
26 amino acids
C121H188N38O32S8
Standard
Sequence
QSHISLCRWCCNCCKANKGCGFCCKF
Physicochemical Analysis
2943.54 Da
8.75
3.77
3.39
0.1448
0.10
0.57
-0.03
70.18
33.85
0.1154
5500.00
6000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1144.98
-13.84
48.0
45.0
96.0
199.0
5.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0105191 VERIFIED: YES
Provenance & Taxonomy
Scophthalmus maximus [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
E. tarda
2 μM
MIC
PaperTurbot (Scophthalmus maximus) hepcidin-1 and hepcidin-2 possess antimicrobial activity and promote resistance against bacterial and viral infection.
RECORD: Rec_0157181 VERIFIED: YES
Provenance & Taxonomy
Scophthalmus maximus [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Micrococcus luteus
1 μM
MIC
PaperTurbot (Scophthalmus maximus) hepcidin-1 and hepcidin-2 possess antimicrobial activity and promote resistance against bacterial and viral infection.
RECORD: Rec_0200358 VERIFIED: YES
Provenance & Taxonomy
Scophthalmus maximus [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Vibrio anguillarum C312
04-8 μM
MIC
PMID24647314 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24647314/
RECORD: Rec_0203330 VERIFIED: YES
Provenance & Taxonomy
Actinopterygii [Animal]
7898
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID24275143 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24275143/
RECORD: Rec_0321160 VERIFIED: YES
Provenance & Taxonomy
Scophthalmus maximus [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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