Peptide Database

Peptide NameVicilin-like Antimicrobial peptide 2c-3 (MiAMP2c-3; Plant defensin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC358H583N129O121S6

DescriptionStandard

        RQRDPQQQYEQCQKRCQRRETEPRHMQICQQRCERRYEKEKRKQQKRYEEQQREDEEKYEERMKEGD
    

Molecular Weight8822.64 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)2.84

Net Charge (pH 7.4) 2.49

Charge Density (pH 7.0) 0.0424

GRAVY Index-2.82

Hydrophobic Moment 0.62

Boman Index-0.94

Instability Index82.41

Aliphatic Index 5.82

Aromaticity 0.0597

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6210.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4320.37

LogP -50.98

H-bond Donors 153.0

H-bond Acceptors 131.0

Rotatable Bonds 324.0

Heavy Atoms 614.0

Ring Count 7.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409284 VERIFIED: YES

Provenance & Taxonomy

OrganismMacadamia integrifolia [Plant]

FamilyDefensin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Antifungal

TargetCeratocystis paradoxa

Activity20-50 μg/mL

MethodIC50

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