Peptide Database

Peptide NameSLAY-screened peptide P2334

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC117H175N35O27S

DescriptionStandard

        IHPHLLHCKNLFTRYNKYTH
    

Molecular Weight2535.92 Da

Isoelectric Point (pI)9.63

Net Charge (pH 7.0)3.09

Net Charge (pH 7.4) 2.67

Charge Density (pH 7.0) 0.1547

GRAVY Index-0.82

Hydrophobic Moment 0.52

Boman Index-0.11

Instability Index18.05

Aliphatic Index 78.00

Aromaticity 0.1500

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1003.19

LogP -6.73

H-bond Donors 36.0

H-bond Acceptors 35.0

Rotatable Bonds 79.0

Heavy Atoms 180.0

Ring Count 8.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0000969 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/