Peptide Database

Peptide NameIdarucizumab

Function Ontology

Hemostasis ▸ Anticoagulant activity

Standard StatusStandard

Sequence Length225 amino acids

Chemical FormulaC1065H1645N271O334S5

DescriptionStandard

        QVQLQESGPGLVKPSETLSLTCTVSGFSLTSYIVDWIRQPPGKGLEWIGVIWAGGSTGYNSALRSRVSITKDTSKNQFSLKLSSVTAADTAVYYCASAAYYSYYNYDGFAYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
    

Molecular Weight23749.39 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)4.88

Net Charge (pH 7.4) 4.45

Charge Density (pH 7.0) 0.0217

GRAVY Index-0.05

Hydrophobic Moment 0.62

Boman Index0.14

Instability Index36.26

Aliphatic Index 76.62

Aromaticity 0.1067

Extinction Coeff. Reduced 46870.00

Extinction Coeff. Oxidized 47120.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0140565 VERIFIED: NO

Provenance & Taxonomy

OrganismCricetulus griseus [Animal]

FamilyMonoclonal antibody

Tax ID10029

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide-bonded therapeutic scaffold described in source text

Bio-Activity Profile

Function

Coagulation factor replacement Anticoagulant

TargetCHO

Half-Lifeinitial half-life: 47 minutes terminal half-life: 10.3 h