Peptide Database

Peptide NameColicin-E1*

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length521 amino acids

Chemical FormulaC2518H4111N729O801S8

DescriptionStandard

        METAVAYYKDGVPYDDKGEVIITLLNGNPDGSGSGGGGGTGGSKSESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQHLKDIVNEALRHNSTHPEVIDLLMPIMQRCRQKQSGCALQKQKKKPVKKRKRAEKSFQEAEQRRKEIEKEQAETERQLKLAEDEEKRLAALSEEARAVEVAQKNLAAAQSELAKVDEEINTLNTRLSSSIHARDAETNTLSGKRNELDQASAKYKELDERVKLLSPRANDPLQSRPFFEATRLRARRGDEMEEKQKQVTATETRLNQISSEINGIQEAISQANNKRSTAVSRIHDAEDNLKTAQTNLLNSQIKDAVDATVSFYQTLSEKYGEKYSKMAQELADKSKGKKISNVNEALAAFEKYKDVLNKKFSKADRDAIFNALEAVKYEDWAKHLDQFAKYLKITGHVSFGYDVVSDILKIKDTGDWKPLFLTLEKKAVDAGVSYVVVLLFSVLAGTTLGIWGIAIVTGILCAFIDKNKLNTINEVLGI
    

Molecular Weight57669.50 Da

Isoelectric Point (pI)8.95

Net Charge (pH 7.0)8.26

Net Charge (pH 7.4) 7.39

Charge Density (pH 7.0) 0.0159

GRAVY Index-0.62

Hydrophobic Moment 0.73

Boman Index-0.14

Instability Index35.36

Aliphatic Index 82.71

Aromaticity 0.0537

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40005.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0223584 VERIFIED: NO

Provenance & Taxonomy

OrganismShigella sonnei [Bacterium]

FamilyChannel forming colicin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli