Peptide Database

Peptide NameSLAY-screened peptide P2834

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC91H117N19O19S

DescriptionStandard

        MLWWTHKYYDWLA
    

Molecular Weight1813.08 Da

Isoelectric Point (pI)6.49

Net Charge (pH 7.0)-0.41

Net Charge (pH 7.4) -0.69

Charge Density (pH 7.0) -0.0319

GRAVY Index-0.41

Hydrophobic Moment 0.27

Boman Index0.27

Instability Index71.30

Aliphatic Index 67.69

Aromaticity 0.3846

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 612.58

LogP 2.10

H-bond Donors 23.0

H-bond Acceptors 21.0

Rotatable Bonds 51.0

Heavy Atoms 130.0

Ring Count 9.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0162904 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/