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MYP_171112
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Basic Information
D-RTH-D-sh-Buforin
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
20 amino acids
C106H181N41O23
Standard
Sequence
RTHRAGLQFPVGRVHRLLRK
Physicochemical Analysis
2397.83 Da
12.00
5.93
5.63
0.2967
-0.75
0.81
-0.38
46.67
92.50
0.0500
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1063.63
-9.89
40.0
31.0
80.0
170.0
4.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0208973 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli MG1655
4 μM
MIC
PMID25891844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25891844/
RECORD: Rec_0330816 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human embryonic kidney HEK293 cells ( at NA , Human erythrocytes (4.9+-0.5% Hemolysis at 32 microM, Human erythrocytes (4.2+-0.3% Hemolysis at 2 microM, Human embryonic kidney HEK293 cells (5% Killing at 128 microM
293 μM
Hemolysis
PMID25891844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25891844/
RECORD: Rec_0370757 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli MG1655 del-recA
2 μM
MIC
PMID25891844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25891844/
RECORD: Rec_0377852 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella aerogenes ATCC 13048
32 μM
MIC
PMID25891844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25891844/
RECORD: Rec_0390058 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli MG1655
32 μM
MIC
PMID25891844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25891844/
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