Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length197 amino acids

Chemical FormulaC1005H1530N224O298S8

DescriptionStandard

        IDDLAEIDYSLNSLPAVFQPFIDLDLKGIVYPAGNYTGLPYVAAPFTIPDQSNSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEEVKSGKKIVFSFLLQTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNVAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight21774.74 Da

Isoelectric Point (pI)4.14

Net Charge (pH 7.0)-11.24

Net Charge (pH 7.4) -11.52

Charge Density (pH 7.0) -0.0571

GRAVY Index0.38

Hydrophobic Moment 0.55

Boman Index0.27

Instability Index42.45

Aliphatic Index 98.53

Aromaticity 0.1371

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8265.85

LogP -96.05

H-bond Donors 280.0

H-bond Acceptors 295.0

Rotatable Bonds 697.0

Heavy Atoms 1535.0

Ring Count 38.0

Amide Bonds 213.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0322228 VERIFIED: NO

Provenance & Taxonomy

OrganismHerpetotheres cachinnans (Laughing falcon) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria