Peptide Database

Peptide NameSLAY-screened peptide P4691

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC37H58N12O12

DescriptionStandard

        LQHETVH
    

Molecular Weight862.93 Da

Isoelectric Point (pI)5.98

Net Charge (pH 7.0)-1.06

Net Charge (pH 7.4) -1.37

Charge Density (pH 7.0) -0.1518

GRAVY Index-0.87

Hydrophobic Moment 0.16

Boman Index-0.04

Instability Index55.14

Aliphatic Index 97.14

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 395.90

LogP -3.55

H-bond Donors 13.0

H-bond Acceptors 13.0

Rotatable Bonds 27.0

Heavy Atoms 61.0

Ring Count 2.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0007788 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/