Peptide Database

Peptide NameDybowskin-2CDYb

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC331H536N104O103S3

DescriptionStandard

        MFTLKKSLLLLFFLGTISLSLCEEERNADDDERRDDPDEMDVEVENRSAVGRHSRRFGLRKHRKH
    

Molecular Weight7716.63 Da

Isoelectric Point (pI)6.27

Net Charge (pH 7.0)-1.22

Net Charge (pH 7.4) -1.63

Charge Density (pH 7.0) -0.0188

GRAVY Index-0.88

Hydrophobic Moment 0.70

Boman Index-0.32

Instability Index48.66

Aliphatic Index 76.46

Aromaticity 0.0615

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3414.14

LogP -34.67

H-bond Donors 123.0

H-bond Acceptors 108.0

Rotatable Bonds 270.0

Heavy Atoms 541.0

Ring Count 8.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0335315 VERIFIED: NO

Provenance & Taxonomy

OrganismRana dybowskii [Animal]

FamilyFrog skin active peptide (FSAP)

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence