Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length265 amino acids

Chemical FormulaC1353H2056N304O395S12

DescriptionStandard

        CKLEALWMLSELLTRNPNTSLCPEALAWPFPFSVLMPIDDLAEVDYSLNSLPAVFQPFIDLDLKGIVYPAGNYSGPPFVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEVFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight29285.38 Da

Isoelectric Point (pI)4.10

Net Charge (pH 7.0)-17.15

Net Charge (pH 7.4) -17.53

Charge Density (pH 7.0) -0.0647

GRAVY Index0.38

Hydrophobic Moment 0.55

Boman Index0.27

Instability Index49.95

Aliphatic Index 100.15

Aromaticity 0.1283

Extinction Coeff. Reduced 27390.00

Extinction Coeff. Oxidized 27640.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148564 VERIFIED: NO

Provenance & Taxonomy

OrganismNipponia nippon [Animal]

FamilyBPI/LBP

Tax ID128390

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria