Peptide Database

Peptide Name[Arg16]chicken secretin

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC138H219N41O41S2

DescriptionStandard

        HSDGLFTSEYSKMRGRAQVQKFIQNLM
    

Molecular Weight3172.60 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)1.85

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.0685

GRAVY Index-0.69

Hydrophobic Moment 0.55

Boman Index-0.15

Instability Index20.11

Aliphatic Index 57.78

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1372.55

LogP -14.86

H-bond Donors 48.0

H-bond Acceptors 46.0

Rotatable Bonds 110.0

Heavy Atoms 222.0

Ring Count 4.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409034 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetPAC1 receptor (Rat); PAC1 receptor (Human); secretin receptor (Rat)

Activity20000 nM

MethodIC50