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MYP_170905
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Basic Information
MP-VB1 (Insects, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C65H120N18O17S
Standard
Sequence
INMKASAAVAKKLL
Physicochemical Analysis
1457.82 Da
10.30
2.76
2.55
0.1969
0.67
0.43
0.16
3.22
132.86
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
583.00
-4.42
20.0
21.0
52.0
101.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0250014 VERIFIED: YES
Provenance & Taxonomy
Vespa bicolor [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli ATCC 25922, Escherichia coli 23A
15 μg/mL
MIC
PaperAntimicrobial peptides from the venoms of Vespa bicolor Fabricius..
RECORD: Rec_0262749 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Rabbit erythrocytes
200 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/18723059/ PMID18723059 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18723059/
RECORD: Rec_0294580 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0299740 VERIFIED: YES
Provenance & Taxonomy
Vespa bicolor [Animal]
MP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperPeptides. 2008 Nov;29(11):1887-92 | http://www.ncbi.nlm.nih.gov/pubmed/18723059 PMID18723059 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18723059/
RECORD: Rec_0375684 VERIFIED: YES
Provenance & Taxonomy
Vespa bicolor [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 2002
15 μg/mL
MIC
PaperAntimicrobial peptides from the venoms of Vespa bicolor Fabricius..
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