Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length230 amino acids

Chemical FormulaC1164H1774N264O352S8

DescriptionStandard

        IDDLAEVDYSLSSFPAVFQPFIDLDLKAIFPAGNYTGSPYMVVPFTVTDQSDSMLFLAFSEYFFQTSSFAYYTTGAFNMTIAEEVSRTQSYFNISTEIFGSIIAEAAKYSVTPYPVMLKLMATEIPVISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTVNVAANSSISLNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight25354.61 Da

Isoelectric Point (pI)4.09

Net Charge (pH 7.0)-15.13

Net Charge (pH 7.4) -15.45

Charge Density (pH 7.0) -0.0658

GRAVY Index0.36

Hydrophobic Moment 0.53

Boman Index0.25

Instability Index51.86

Aliphatic Index 97.52

Aromaticity 0.1304

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 14900.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0162707 VERIFIED: NO

Provenance & Taxonomy

OrganismPiprites chloris [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria