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MYP_170875
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Basic Information
Antifungal protein ginkbilobin-1 (Ginkbilobin) (GNL)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-HIV
Binding / Molecular interaction ▸ Carbohydrate-binding peptide ▸ Lectin
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
40 amino acids
C183H291N59O54S
Standard
Sequence
ANTAFVSSAHNTQKIPAGAPFNRNLRAMLADLRQNAAFAG
Physicochemical Analysis
4213.70 Da
11.71
2.88
2.64
0.0721
-0.18
0.61
0.02
37.12
71.25
0.0750
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1840.89
-23.89
62.0
59.0
135.0
297.0
6.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0199292 VERIFIED: YES
Provenance & Taxonomy
Ginkgo biloba [Plant]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral Antifungal
Rhizoctonia solani
PaperPubMed PMID: 11118300 PMID11118300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11118300/
RECORD: Rec_0208031 VERIFIED: YES
Provenance & Taxonomy
Ginkgo biloba [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral Anti-HIV
Rhizoctonia solani
PMID11118300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11118300/
RECORD: Rec_0213099 VERIFIED: YES
Provenance & Taxonomy
Ginkgo biloba [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral Anti-Gram-positive Anti-Gram-negative
Coprinus comatus
PMID11118300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11118300/
RECORD: Rec_0251766 VERIFIED: NO
Provenance & Taxonomy
Ginkgo biloba [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
1 adjusted p-value (4.5 h)
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0260778 VERIFIED: YES
Provenance & Taxonomy
Ginkgo biloba [Plant]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral Antifungal
Pseudomonas aeruginosa
PaperPubMed PMID: 11118300 PMID11118300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11118300/
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