Peptide Database

Peptide NameNeurotrophin-4

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length130 amino acids

Chemical FormulaC592H952N194O184S6

DescriptionStandard

        GVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA
    

Molecular Weight13923.47 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)3.82

Net Charge (pH 7.4) 3.45

Charge Density (pH 7.0) 0.0294

GRAVY Index-0.41

Hydrophobic Moment 0.68

Boman Index-0.11

Instability Index59.45

Aliphatic Index 68.31

Aromaticity 0.0615

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6117.33

LogP -74.96

H-bond Donors 229.0

H-bond Acceptors 195.0

Rotatable Bonds 457.0

Heavy Atoms 976.0

Ring Count 17.0

Amide Bonds 133.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0163316 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyNGF-beta family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide17-90; 61-119; 78-121

Bio-Activity Profile

Function

Cytokine Growth factor NGF-beta family Growth factor signaling