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MYP_170848
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Basic Information
Kasseptin 1Mc
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
20 amino acids
C93H154N24O23
Standard
Sequence
FVGAIAAALPHVISAIKNAL
Physicochemical Analysis
1976.36 Da
8.76
0.85
0.59
0.0423
1.49
0.51
0.55
6.39
156.50
0.0500
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
725.45
-4.39
24.0
25.0
61.0
140.0
3.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009230 VERIFIED: YES
Provenance & Taxonomy
Kassina maculata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse erythrocytes
16 μM
Hemolysis
PMID19427345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19427345/
RECORD: Rec_0022688 VERIFIED: YES
Provenance & Taxonomy
Kassina maculata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Toxicity
Staphylococcus aureus. At the same concentration, the peptide can cause hemolysis (horse blood) by ~50%. UPdated 5/2020
PaperA family of kassinatuerin-2 related peptides from the skin secretion of the African hyperoliid frog, Kassina maculata.
RECORD: Rec_0052573 VERIFIED: YES
Provenance & Taxonomy
Kassina maculata [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
PaperPubMed PMID: 19427345 PMID19427345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19427345/
RECORD: Rec_0123427 VERIFIED: NO
Provenance & Taxonomy
Kassina maculata [Animal]; Hylambates maculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0210954 VERIFIED: YES
Provenance & Taxonomy
Kassina maculata [Animal]
Kasseptin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
PaperL. Wang et al. / Peptides 30 (2009) 1428-1433. A family of kassinatuerin-2 related peptides from the skin secretion of the African hyperoliid frog, Kassina maculata Evidence URLhttps://www.uniprot.org/uniprotkb/C7C1L0/entry
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