Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC553H880N146O167S5

DescriptionStandard

        PDLSGYEKFGLGNVKYNMSRIHVTAVEFPSASISLIPGTGIKLVIGNASLTIDMNWNIRTWMFKDSGRSTVYISKVFVTAIFSTPLDNMGHTSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12406.11 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)3.13

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index0.04

Hydrophobic Moment 0.48

Boman Index0.13

Instability Index16.89

Aliphatic Index 89.74

Aromaticity 0.0877

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5016.64

LogP -54.85

H-bond Donors 180.0

H-bond Acceptors 177.0

Rotatable Bonds 410.0

Heavy Atoms 871.0

Ring Count 18.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192124 VERIFIED: NO

Provenance & Taxonomy

OrganismOceanites oceanicus (Wilson`s storm petrel) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria