Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length243 amino acids

Chemical FormulaC1254H1896N278O364S8

DescriptionStandard

        IDDLAEVDYSLNSLPAVFQPFIDLDLKGIVYPAGNYTGPPYVAAPFTVPDESDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEEAKSGKLFYLFFFFLQTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNIAANTSIALNIFDQKLMGSLCLNRLRFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight26946.63 Da

Isoelectric Point (pI)4.22

Net Charge (pH 7.0)-14.14

Net Charge (pH 7.4) -14.49

Charge Density (pH 7.0) -0.0582

GRAVY Index0.39

Hydrophobic Moment 0.55

Boman Index0.28

Instability Index46.38

Aliphatic Index 100.78

Aromaticity 0.1440

Extinction Coeff. Reduced 19370.00

Extinction Coeff. Oxidized 19495.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0399528 VERIFIED: NO

Provenance & Taxonomy

OrganismPhoenicopterus ruber ruber [other]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria