MYP_170774
Wollamide B [l3D-Phe(4Cl), V4I, N5D-Orn]
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
▸
Antibacterial
Toxicity / Safety
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Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
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General toxin
▸
Cytotoxic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
WLXIXX
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0001575
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
x(3)=D-4-Cl-Phe; x(5)=D-Orn; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic
RECORD: Rec_0151231
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
x(3)=D-4-Cl-Phe; x(5)=D-Orn; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial
Anticancer
HepG2
100 μM
IC50
RECORD: Rec_0189896
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 3,5,6
Bio-Activity Profile
Antimicrobial
Antibacterial
Human hepatocellular carcinoma HepG2
100 μM
IC50
RECORD: Rec_0202112
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 3,5,6
Bio-Activity Profile
Antimicrobial
Antibacterial
Mycobacterium tuberculosis H37Rv
17.5 μM
MIC
RECORD: Rec_0427319
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
x(3)=D-4-Cl-Phe; x(5)=D-Orn; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic