Peptide Database

Peptide NameSLAY-screened peptide P916

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC65H100N20O24

DescriptionStandard

        SRNSFDTTSHPIPS
    

Molecular Weight1545.61 Da

Isoelectric Point (pI)6.46

Net Charge (pH 7.0)-0.45

Net Charge (pH 7.4) -0.71

Charge Density (pH 7.0) -0.0323

GRAVY Index-1.09

Hydrophobic Moment 0.42

Boman Index-0.19

Instability Index39.58

Aliphatic Index 27.86

Aromaticity 0.0714

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 716.39

LogP -11.69

H-bond Donors 25.0

H-bond Acceptors 25.0

Rotatable Bonds 45.0

Heavy Atoms 109.0

Ring Count 4.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0314489 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/