‹ ›
MYP_170766
← PREVIOUS NEXT → BACK
Basic Information
Brevinin-1SPa (Frogs, amphibians, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
24 amino acids
C126H206N28O27S3
Standard
Sequence
FFPIIAGMAAKLIPSLFCKITKKC
Physicochemical Analysis
2641.35 Da
9.70
3.74
3.50
0.1557
1.07
0.59
0.37
22.50
110.00
0.1250
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
859.58
-2.24
31.0
34.0
86.0
184.0
5.0
23.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0007085 VERIFIED: YES
Provenance & Taxonomy
Rana septentrionalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
PMID15556063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15556063/
RECORD: Rec_0012055 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Toxic Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0035182 VERIFIED: YES
Provenance & Taxonomy
Rana septentrionalis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli, Staphylococcus aureus, and Candida albicans
3-13 μM
MIC
PaperPurification and characterization of antimicrobial peptides from the skin secretions of the mink frog (Rana septentrionalis).
RECORD: Rec_0035813 VERIFIED: YES
Provenance & Taxonomy
Rana septentrionalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
13 μM
MIC
PMID15556063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15556063/
RECORD: Rec_0038674 VERIFIED: NO
Provenance & Taxonomy
Rana septentrionalis [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Hemolytic
1 2 3 ... 5 NEXT LAST
Showing 5 records on this page · Page 1 of 5