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MYP_170674
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Basic Information
WN82
Antimicrobial
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-West Nile virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Standard
19 amino acids
C84H129N25O26
Standard
Sequence
VVDRGWGNGAGLFGKGSID
Physicochemical Analysis
1905.07 Da
6.11
-0.26
-0.48
-0.0138
-0.09
0.45
0.17
-31.62
76.84
0.1053
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
828.75
-9.49
29.0
26.0
62.0
135.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0083572 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
West Nile virus (Virus entry); LLC-MK2
4 %
Plaque assay
PaperPeptide inhibitors of dengue virus and West Nile virus infectivity. | Hrobowski YM, Garry RF, Michael SF. | Virol J. 2005 | PMID:15927084 PMID15927084 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15927084/
RECORD: Rec_0159113 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-WNV Fusion inhibition
West Nile virus (WNV) | epithelial cells
52.5 μM
% inhibition
Mammalian: 100 h; Yeast: >20 h; E. coli: >10 h
PaperPeptide derivatives as inhibitors of NS2B-NS3 protease from Dengue, West Nile, and Zika flaviviruses. | da Silva-Júnior EF, de Araújo-Júnior JX. | Bioorg Med Chem. 2019 Sep 15;27(18):3963-3978. | DOI:10.1016/j.bmc.2019.07.038 | PMID:31351847 PMID31351847 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31351847/
RECORD: Rec_0216851 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0218638 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
West Nile virus(WNV)
PMID31351847 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31351847/