Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length480 amino acids

Chemical FormulaC2342H3683N611O687S18

DescriptionStandard

        MQCCLDSAGAPRVRWFTVVRCPHYNLLHGPTRQVTAGAMSLWCVTVALLGLLTPALSTDPGVIVQLTQQGLEYGRQIGIASLQQKLNSIKIPDISGSEDVSPIGKVEYSLSQMHITNLGLPASSLGLVPGSGLSLSISDAFISLNGHWHVKYLKFIKDSGSFDLTVSGLTISVTMGVNSDETGRPTVSSSNCAASVGHVSIEFHGGASWLYNLFSSFIENALRSAIQNQICPLVHDAISDINPHLKTMNVLAQVDKYAEIEYSLVTSPVVSNTFIQFSLKGEFYKIGQHQEPPFSAPPFSLPQTNGSMLYLGLSSFIANSAGFVYHNAGVLGLYVTDDMIPSSSPLRLNTKTFGAFIPEIAKRFPNMMMKLLVKTLEPPRITFEPNNVTLQANGTVTAYAILPNNTLEALFILNLEASVSAELHVSGLNIAGSVTLNRSVHMYLQQGYPLPAISHMNLVNTQLKVLKDYILVGTDVHFTQ
    

Molecular Weight51968.15 Da

Isoelectric Point (pI)6.42

Net Charge (pH 7.0)-3.22

Net Charge (pH 7.4) -4.37

Charge Density (pH 7.0) -0.0067

GRAVY Index0.19

Hydrophobic Moment 0.70

Boman Index0.19

Instability Index39.85

Aliphatic Index 101.73

Aromaticity 0.0813

Extinction Coeff. Reduced 44350.00

Extinction Coeff. Oxidized 44725.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0070758 VERIFIED: NO

Provenance & Taxonomy

OrganismScleropages formosus [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence