Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC525H858N146O146S7

DescriptionStandard

        MKLLLIIAILLFQKSTVTEQLKRCWGEYIRGYCRKICKISEIREVLCENGRYCCLNIVELEARKKITKPSRPKPRTYAVTFPQDYDINIENYSRPKANST
    

Molecular Weight11775.77 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)8.45

Net Charge (pH 7.4) 8.11

Charge Density (pH 7.0) 0.0845

GRAVY Index-0.38

Hydrophobic Moment 0.80

Boman Index-0.12

Instability Index46.84

Aliphatic Index 93.60

Aromaticity 0.0900

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4794.99

LogP -40.38

H-bond Donors 175.0

H-bond Acceptors 162.0

Rotatable Bonds 399.0

Heavy Atoms 824.0

Ring Count 15.0

Amide Bonds 107.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0411478 VERIFIED: NO

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyDefensin

Tax ID9685

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence