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MYP_170661
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Basic Information
D-SMAP-29-D2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
28 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
RGLRRLGRKIAHGVKKYGPTVLRXXRXA
Physicochemical Analysis
0.00 Da
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0032075 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
unspecified non-canonical residue at 24,25,27; d-amino acids. x: d-isoleucine
Bio-Activity Profile
Hemolytic
human red blood cells
217 μM
Hemolysis
PMID26795535 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26795535/
RECORD: Rec_0068145 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
unspecified non-canonical residue at 24,25,27; d-amino acids. x: d-isoleucine
Bio-Activity Profile
Antimicrobial Antibacterial Cytotoxic Anti-Gram-positive Anti-Gram-negative
Escherichia coli KCTC 1682
4 μM
MIC
PMID26795535 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26795535/
RECORD: Rec_0128152 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
unspecified non-canonical residue at 24,25,27; d-amino acids. x: d-isoleucine
Bio-Activity Profile
Antimicrobial Antibacterial Cytotoxic Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa KCTC 1637
4 μM
MIC
PMID26795535 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26795535/
RECORD: Rec_0205462 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
unspecified non-canonical residue at 24,25,27; d-amino acids. x: d-isoleucine
Bio-Activity Profile
Antimicrobial Antibacterial Cytotoxic Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus KCTC 1621
4 μM
MIC
PMID26795535 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26795535/
RECORD: Rec_0212934 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
unspecified non-canonical residue at 24,25,27; d-amino acids. x: d-isoleucine
Bio-Activity Profile
Antimicrobial Antibacterial Cytotoxic Anti-Gram-positive Anti-Gram-negative
Salmonella Typhimurium KCTC 1926
2 μM
MIC
PMID26795535 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26795535/
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